Radiation therapy is actively utilized for superficial lesions. External beam radiotherapy for cutaneous lesions utilizes electrons with low transmittance. Conventional electron beam therapy uses Cerrobend blocks for field shaping
however, the Intraoperative Radiotherapy (IORT) applicator offers superior dosimetric characteristics. The dosimetric parameters were measured using 4 and 6 MeV electron beams delivered by a Trilogy linear accelerator, and percent depth dose and lateral dose profiles were compared under the presence of the IORT applicator and Cerrobend block. The dose calculations under various IORT applicator conditions and planning studies were performed using Monte Carlo simulation. Treatment plans for three sites were evaluated in terms of coverage of the planning target volume, dose to the surrounding normal tissue, and beam-on time for two treatment modalities. The results of the measured and calculated dosimetric parameters correspond. Scattered electrons along the IORT applicators resulted in shorter d