PURPOSE: This study examined how the potential health benefits of movement behaviors - physical activity (PA), sedentary time, and sleep - vary by neighborhood perceptions among Latinos. DESIGN: Cross-sectional analysis of baseline data from churchgoing Latino adults participating in an ongoing randomized controlled trial to promote PA. SETTING: East Los Angeles, California, and surrounding neighborhoods. SAMPLE: Sample of 728 churchgoing Latinos (77% female, mean age 52 years). MEASURES: Movement behaviors included self-reported leisure-time PA and sleep duration, and accelerometer-based sedentary time. Survey assessed perceived neighborhood crime safety, traffic safety, aesthetics, and social cohesion. Outcomes included self-reported stress, depressive symptoms, diabetes, and hypertension
and objectively-measured body mass index. ANALYSIS: Linear or logistic regression assessed associations of the movement behaviors with neighborhood measures, and their interactions, in relation to the health outcomes. RESULTS: Sleep was associated with lower perceived stress [B(SE) = -0.41 (0.09), CONCLUSION: Interaction models suggest interventions targeting neighborhood crime safety, aesthetics, and social cohesion may be key for maximizing the health benefits of movement behaviors among Latinos.