Separating trivalent f-block elements remains a central challenge due to their similar ionic radii and chemical behaviors. Historically, these separations have been achieved using single extractants, either alone or in combination with ion exchange chromatography. However, recent studies, including this work, have explored the potential of using synergic combinations of multiple extractants to enhance extraction and separation efficiencies for trivalent actinide separations. This study investigated synergic solvent extraction (SX) systems for extracting and separating americium and curium using three neutral organophosphorus ligands: octyl (phenyl)-