Transcriptional modulation of Porphyromonas gingivalis biofilms on titanium-copper implant surfaces.

• Tác giả: Vinoj Gopalakrishnan, Maria Infant Majula Shifani Mahendran, Dhamodharan Ramaswamy, Vaijayanthi Saravanan
• Ngôn ngữ: eng
• Ký hiệu phân loại: 368.011 Rates
• Thông tin xuất bản: United States : Folia microbiologica , 2025
• Bộ sưu tập: NCBI
• ID: 145053

Tóm tắt

The healthcare sector is currently concerned about infections caused by Porphyromonas gingivalis biofilms due to their high frequency and incidence, particularly in patients with implanted medical devices. This study investigated biofilm formation and biofilm-related gene expression in P. gingivalis on titanium-copper discs and polycarbonate discs. P. gingivalis highly expressed biofilm-related genes were examined using quantitative real-time PCR during biofilm formation on the Ti-Cu surface. SEM analysis revealed various cellular components around the aggregated cells at various stages of biofilm formation. The Ti-Cu surface was colonized by P. gingivalis, as evidenced by biofilm formation levels that varied from ~ 10