A PD-L1 siRNA-Loaded Boron Nanoparticle for Targeted Cancer Radiotherapy and Immunotherapy.

• Tác giả: Guo Chen, Du Cheng, Ke Cheng, Shaohui Deng, Tianwang Guan, Shuai Guo, Lijun Hu, Caiwen Ou, Xiaochun Wan, Wei Xia, Zecong Xiao, Jujian Ye
• Ngôn ngữ: eng
• Ký hiệu phân loại: 546.671 *Boron
• Thông tin xuất bản: Germany : Advanced materials (Deerfield Beach, Fla.) , 2025
• Bộ sưu tập: NCBI
• ID: 148879

Tóm tắt

Although the combination of radiotherapy and immunotherapy is regarded as a promising clinical treatment strategy, numerous clinical trials have failed to demonstrate synergistic effects. One of the key reasons is that conventional radiotherapies inevitably damage intratumoral effector immune cells. Boron Neutron Capture Therapy (BNCT) is a precise radiotherapy that selectively kills tumor cells while sparing adjacent normal cells, by utilizing