History, clinical presentation, therapy, and patient reported outcomes of mucosal lichen planus: a cross-sectional study.

 0 Người đánh giá. Xếp hạng trung bình 0

Tác giả: Katharina Assaf, Julia M Bootsveld, Neda Cramer, Sascha Gerdes, Matthias Goebeler, Claudia Günther, Christian Kromer, Daniel Kromer, Rotraut Mössner, Sabine Sennhenn-Kirchner, Wiebke Sondermann, Dagmar Wilsmann-Theis

Ngôn ngữ: eng

Ký hiệu phân loại:

Thông tin xuất bản: Germany : Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG , 2025

Mô tả vật lý:

Bộ sưu tập: NCBI

ID: 149302

 BACKGROUND AND OBJECTIVES: Mucosal lichen planus (LP) is a chronic inflammatory disease. The patient's journey can be arduous as diagnosis and therapy are challenging. PATIENTS AND METHODS: In this cross-sectional study, a wide range of characteristics of the patient's journey were assessed and evaluated from a total of 72 patients with mucosal LP who were treated in the dermatology departments of six German university medical centers between 02/2022 and 07/2023. RESULTS: On average, 18.1 months elapsed between the onset of symptoms and diagnosis. Until the correct diagnosis was made, an average of 3.1 different physicians of the same or different specialties were consulted. 28.1% of patients also had cutaneous involvement. Therapeutically, 68% of patients received at least one systemic drug. Both topical (90%, 65/72) and systemic (oral, 50% of patients, 36/72
  intravenous, 33%, 24/72) glucocorticoids were most frequently used. Systemic agents were most often discontinued due to ineffectiveness (46%, 50/110). Satisfaction with treatment was highest for intravenous and topical glucocorticoids (moderate to high satisfaction: 59% and 36%, respectively), and lowest for retinoids with 8%. CONCLUSIONS: This study indicates that there might be a lack of diagnostic awareness among physicians and the unmet need for effective systemic treatment options.
Tạo bộ sưu tập với mã QR

THƯ VIỆN - TRƯỜNG ĐẠI HỌC CÔNG NGHỆ TP.HCM

ĐT: (028) 36225755 | Email: tt.thuvien@hutech.edu.vn

Copyright @2024 THƯ VIỆN HUTECH