RATIONALE: The 6 elements of orofacial harmony play a crucial role in establishing individual aesthetics in orthodontics and orthognathic treatments. The use of digital tools streamlines multidisciplinary treatment processes and facilitates the attainment of precise outcomes. PATIENT CONCERNS: The patient required orthodontic treatment because of a convex profile. UR1 was missing because of trauma and was replaced with a fixed bridge. DIAGNOSES: The patient presented with a skeletal Class II relationship and a deep overbite. Diagnosis based on the 6 elements of orofacial harmony identified an overdeveloped maxilla, a relatively normal mandible, and an underdeveloped chin with a vertical growth pattern. INTERVENTIONS: To address these issues, a combined orthodontic and orthognathic treatment plan was implemented with a detailed surgical protocol developed according to these 6 elements. Customized brackets and 3D-printed occlusal plates were used in this study. After completing orthodontic treatment, an anterior prosthesis was designed using 3D digital technology to restore occlusal function and enhance anterior aesthetics. OUTCOMES: Post-treatment, the patient demonstrated reduced facial convexity, a flattened nasolabial sulcus, balanced occlusal forces, and restored occlusal function. LESSONS: The outcomes of this case highlight the crucial role of the 6 elements of orofacial harmony in guiding the design and aesthetic planning of orthodontic and orthognathic treatment. In addition, the use of personalized treatment tools significantly enhances the treatment accuracy.