The deeper genome : why there is more to the human genome than meets the eye

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Tác giả: John Parrington

Ngôn ngữ: eng

ISBN-13: 978-0199688739

Ký hiệu phân loại: 572.86 DNA (Deoxyribonucleic acid)

Thông tin xuất bản: Oxford, United Kingdom : Oxford University Press, 2015.

Mô tả vật lý: v, 246 pages : , illustrations ; , 24 cm

Bộ sưu tập: Khoa học tự nhiên

ID: 152804

 As the Human Genome Project completed its mapping of the entire human genome, hopes ran high that we would rapidly be able to use our knowledge of human genes to tackle many inherited diseases, and understand what makes us unique among animals. But things didn't turn out that way... but the emerging picture is if anything far more exciting. Parrington gives an outline of the deeper genome, involving layers of regulatory elements controlling and coordinating the switching on and off of genes
  the impact of its 3D geometry
  the discovery of a variety of new RNAs playing critical roles
  the epigenetic changes influenced by the environment and life experiences that can make identical twins different and be passed on to the next generation
  and the clues coming out of comparisons with the genomes of Neanderthals as well as that of chimps about the development of our species.-- Source other than the Library of Congress.
Includes bibliographical references (pages 210-236) and indexes.
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