Metabolic engineering of rapidly growing Synechococcus elongatus strains for phototrophic production of alkanes.

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Tác giả: Aditya P Sarnaik, Vaibhav Srivastava, Pramod P Wangikar

Ngôn ngữ: eng

Ký hiệu phân loại: 920.71 Men

Thông tin xuất bản: United States : Biotechnology progress , 2025

Mô tả vật lý:

Bộ sưu tập: NCBI

ID: 159385

 Alkanes are high-energy hydrocarbons that are foreseen as next generation biofuels. Cyanobacteria are known to naturally synthesize C15-C19 alkanes
  however, the titers are too low to make this a commercially viable process. Therefore, to leverage these photosynthetic platforms for improved alkane production, here we engineered three novel isolates of Synechococcus elongatus PCC 11801, PCC 11802, and IITB6. The two gene AAR-ADO alkane biosynthesis pathway was constructed by cloning the genes for acyl-ACP reductase (aar) and aldehyde deformylating oxygenase (ado) from S. elongatus PCC 7942 under the regulation of P
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