Soleus muscle necrosis is a rare complication following fibula free flap harvest for mandibular reconstruction. This report presents a case of soleus necrosis without compartment syndrome or infection and reviews the blood supply of the soleus muscle in 24 patients. Variations in the vascular anatomy of the soleus muscle, particularly reliance on the peroneal artery, may predispose to this complication. Clinicians should consider soleus muscle necrosis in patients with atypical donor site pain after fibula harvest. Laryngoscope, 135:1083-1085, 2025.