Line-dropped gelatin multi-element calibration standards in LA-ICP-MS: a statistically verifying comparison with cryosectioned homogenized lung and liver as matrix-matched calibration standards and as corresponding reference materials.

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Tác giả: Ruth Becker, Jens Bertram, Danny Jonigk, Thomas Kraus, Manfred Möller, Thomas Schettgen, Sven Thoröe-Boveleth, Ralf Weiskirchen

Ngôn ngữ: eng

Ký hiệu phân loại: 368.12 *Allied fire insurance lines and extended coverage endorsement

Thông tin xuất bản: Switzerland : Analytical sciences : the international journal of the Japan Society for Analytical Chemistry , 2025

Mô tả vật lý:

Bộ sưu tập: NCBI

ID: 159717

Calibrations in LA-ICP-MS are typically very time-consuming and complex, as they need to be matched to the samples being measured and sectioned on a microtome. Alternatively, gelatin can be in droplet form or as a section, which is a more recent development. In this study, we report on investigations where hot multi-element gelatin solutions are placed in a linear fashion on microscopic slides to conduct comparative statistical observations between doped tissue homogenates from the liver and lung. The tissue homogenates served as both samples (complete ablation) and calibration standards (partial ablation) for verification purposes. We explored the effects of different laser fluences (0.50-1.50 J/cm
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