Tumor Microenvironment-Responsive Multinucleated Nanocomplexes Loaded with Carbon Dots for Combined Photothermal/Chemodynamic Therapy of Breast Cancer.

• Tác giả: Wei Bian, Cui He, Yimin Jin, Xinjing Tang, Jing Wang, Yan Zhang, Zihan Zhu
• Ngôn ngữ: eng
• Ký hiệu phân loại: 787.86 *Vihuelas
• Thông tin xuất bản: Germany : ChemMedChem , 2025
• Bộ sưu tập: NCBI
• ID: 160451

Tóm tắt

Low cure rate and high death rate of cancers have seriously threatened human health. The combining multiple therapies is a promising strategy for cancer treatment. In this study, we construct a novel multinucleated nanocomplex loaded with carbon dots (CDs-SA@TAMn) that responds to tumor microenvironment for combined photothermal/chemodynamic cancer therapy. Fluorescence imaging results show that CDs-SA@TAMn can effectively accumulated in tumor sites. In acidic tumor microenvironment, CDs-SA@TAMn will release Mn