Lactoferrin-functionalized PEGylation liposomes loaded with norcantharidin acid for targeted therapy of hepatocellular carcinoma.

• Tác giả: Shunqiao Cai, Hongxia Fan, Jingxin Gou, Haibing He, Yuxin Liu, Yinling Mu, Xing Tang, Mingli Wei, Tian Yin, Jingjing Yuan, Yu Zhang
• Ngôn ngữ: eng
• Thông tin xuất bản: Netherlands : International journal of pharmaceutics , 2025
• Bộ sưu tập: NCBI
• ID: 160615

Tóm tắt

Norcantharidin (NCTD), an antitumor agent with an increased leukocyte function, has been used for the treatment of hepatocellular carcinoma (HCC) in clinical. However, the clinical application of NCTD is limited due to its inadequate hydrophilicity and lipophilicity, short half-life (t