Formulation, development and in vivo characterization of selegiline hydrochloride nanostructured lipid nanocarrier loaded microneedle array patch for depression.

• Tác giả: Anuradha Patil, Atmaram Pawar, Amarjitsing Rajput, Praveen Subbappa
• Ngôn ngữ: eng
• Ký hiệu phân loại: 344.023 *Old age and survivors insurance
• Thông tin xuất bản: Netherlands : International journal of pharmaceutics , 2025
• Bộ sưu tập: NCBI
• ID: 160699

Tóm tắt

Depression is a common mental condition causing depressed mood and loss of pleasure. The primary treatment approach for the management of depression consists of the use of selegiline (MAO-B) inhibitor compound. The present work aimed to develop and optimize selegiline-loaded nanostructured lipid carriers for transdermal application, utilizing a 2