Modeling and simulating cardiac electrical activity

• Tác giả: David J Christini, Trine Krogh-Madsen
• Ngôn ngữ: eng
• ISBN-13: 978-0750320627
• ISBN-13: 978-0750320634
• ISBN-13: 978-0750320641
• ISBN-13: 978-0750320658
• Ký hiệu phân loại: 612.171 Biophysics
• Thông tin xuất bản: Bristol [England] (Temple Circus, Temple Way, Bristol BS1 6HG, UK) : IOP Publishing, 2020
• Mô tả vật lý: 1 online resource (various pagings) : , illustrations (some color).
• Bộ sưu tập: Tài liệu truy cập mở
• ID: 160919
• Chủ đề: 1. Heart--Electric properties; 3. Biophysics; 4. SCIENCE / Life Sciences / Biophysics; 5. Heart Conduction System--physiology; 6. Electrocardiography; 7. Models, Theoretical

Includes bibliographical references.

Tóm tắt

This book provides a thorough introduction to the topic of mathematical modeling of electrical activity in the heart, from molecular details of ionic channel dynamics to clinically derived patient-specific models. It discusses how cellular ionic models are formulated, introduces commonly used models and explains why there are so many different models available. The chapters cover modeling of the intracellular calcium handling that underlies cellular contraction as well as modeling molecular-level details of cardiac ion channels, and also focus on specialized topics such as cardiomyocyte energetics and signalling pathways. It is an excellent resource for experienced and specialised researchers in the field, but also biological scientists with a limited background in mathematical modelling and computational methods. Part of Biophysical Society-IOP series.