This paper re-examines the problem of estimating risk premia in linear factor pricing models. Typically, the data used in the empirical literature are characterized by weakness of some pricing factors, strong cross-sectional dependence in the errors, and (moderately) high cross-sectional dimensionality. Using an asymptotic framework where the number of assets/portfolios grows with the time span of the data while the risk exposures of weak factors are local-to-zero, we show that the conventional two-pass estimation procedure delivers inconsistent estimates of the risk premia. We propose a new estimation procedure based on sample-splitting instrumental variables regression. The proposed estimator of risk premia is robust to weak included factors and to the presence of strong unaccounted cross-sectional error dependence. We derive the many-asset weak factor asymptotic distribution of the proposed estimator, show how to construct its standard errors, verify its performance in simulations, and revisit some empirical studies.