Effect of Gadolinium Doping on the Optical and Magnetic Properties of Red-Emitting Dual-Mode Carbon Dot-Based Probes for Magnetic Resonance Imaging.

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Tác giả: Ivan A Aleinik, Zilya F Badrieva, Ekaterina A Brui, Arina A Efimova, Aleksandra V Koroleva, Yingqi Liang, Mikhail D Miruschenko, Alexander M Mitroshin, Songnan Qu, Andrey L Rogach, Evgeniia A Stepanidenko, Elena V Ushakova, Olga V Volina, Evgeniy V Zhizhin

Ngôn ngữ: eng

Ký hiệu phân loại: 538.36 Magnetic resonance

Thông tin xuất bản: United States : ACS applied bio materials , 2025

Mô tả vật lý:

Bộ sưu tập: NCBI

ID: 163610

Bioimaging probes based on carbon dots (CDs) can become a useful replacement for existing commercial probes, benefiting clinical diagnostics. While the development of dual-mode CD-based probes for magnetic resonance imaging (MRI), which provides the ability for photoluminescence (PL) detection at the same time, is ongoing, several challenges have to be addressed. First, most of the CD-based probes still emit at shorter wavelengths (blue/green spectral range), which is harmful to biological objects or have very low PL intensity in the biological window of tissue transparency (red/near-infrared spectral range). Second, the relaxation characteristics of the proposed CD-based probes are still similar or only slightly larger than those of commercial contrast agents. Herein, we introduce a dual-mode probe allowing for simultaneous PL detection and MRI analysis, based on CDs doped with gadolinium ions (Gd
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