Radiosynthesis and in vivo evaluation of [

• Tác giả: Anthony P Belanger, Matthew Crouthamel, Rizwana Islam, Charalambos Kaittanis, Hyunjung Kim, Ashley Knight, Paul McQuade, Meera Modi, Madhu Natarajan, Nikolaos Papaioannou, Yoann Petibon, Wanida Ruangsiriluk, Johannes Tauscher, Tyler Teceno, Christopher T Winkelmann, Zhaoming Xiong
• Ngôn ngữ: eng
• Ký hiệu phân loại: 912.01 Philosophy and theory
• Thông tin xuất bản: England : Bioorganic & medicinal chemistry letters , 2025
• Bộ sưu tập: NCBI
• ID: 165022

Tóm tắt

Changes in metabolism are associated with several prevalent and rare diseases, like Hunter syndrome (MPS II). These alterations result in changes in mitochondrial function, therefore having non-invasive imaging biomarkers to detect this pathophysiological hallmark is a key objective of translational medicine. Here we report the synthesis and in vivo evaluation of the [