Are corticosteroids in intensive care immunosuppressive? Reflections and hypotheses.

• Tác giả: Rayan Braïk
• Ngôn ngữ: eng
• Ký hiệu phân loại: 616.123028 Diseases of cardiovascular system
• Thông tin xuất bản: France : Anaesthesia, critical care & pain medicine , 2025
• Bộ sưu tập: NCBI
• ID: 165720

Tóm tắt

This review reconsiders the classification of corticosteroids as immunosuppressants in the management of acute inflammatory conditions in critical care. Despite their widespread use in ARDS and septic shock, the association between corticosteroid therapy and increased infection risk remains contentious. By exploring alternative mechanisms and presenting new hypotheses, this review suggests that the traditional view of corticosteroids as immunosuppressants may be overly simplistic and context dependent.