Global crop productivity is consistently threatened by cadmium (Cd) soil contamination. Crosstalk between nitric oxide (NO) and melatonin (MT) in enhancing crop resilience to heavy metal stress has gained significant attention. Here, we evaluated the joint effect of sodium nitroprusside (SNP
200 μM as NO donor) and MT (100 μM) on Cd-stressed eggplant (Solanum melongena L.). Cd stress significantly reduced plant growth, biomass yield, leaf pigments, and biochemical properties. Conversely, SNP, MT, and particularly their combined (SNP + MT) application reduced Cd toxicity and enhanced growth and physio-biochemical traits of eggplants. For instance, at 50 mg Cd kg