The supraclavicular artery island flap(SCAIF)is a pedicled fasciocutaneous flap primarily based on the supraclavicular artery and vein. It is commonly utilized in head and neck cancer reconstructive surgery due to its extensive reach, vascular reliability, and simple harvesting technique. This report presents three cases in which SCAIF was employed for soft tissue reconstruction following oral cancer resections. In Case 1, an 80-year-old female patient with right maxillary gingival carcinoma (cT3N2bM0)underwent tracheostomy, right modified radical neck dissection(MRND), partial maxillectomy, and reconstruction using SCAIF. Case 2 involved a 63-year-old male patient diagnosed with left tongue carcinoma(cT2N1M0), who underwent tracheostomy, left MRND, partial glossectomy, and SCAIF reconstruction. In Case 3, a 73-year-old female patient with right lower gingival carcinoma(cT3N2bM0)underwent tracheostomy, bilateral neck dissection, marginal mandibulectomy, and SCAIF reconstruction. In all cases, postoperative wound healing was satisfactory. The SCAIF proved to be a valuable option for reconstructing soft tissue defects after oral cancer surgery, resulting in reliable outcomes and functional restoration.