World Health Organization priority antimicrobial resistance in

• Tác giả: Luiz F Abreu Guimarães, Marcelle D Alves, Laura C Antochevis, Beatriz Arns, Afonso L Barth, Daniela S Cappa, Anna Carla Castiñeiras, André A M Coelho, Erika E de A Sousa, Francieli P de Almeida, Antonio G N D de Melo, Paulo C P de Sousa, Ândrea C Dos Santos, Adriana L P Ferreira, Lígia L Frutuoso, Evelyne S Girão, Ricardo D Guzman, Danielle M Henrique, Robson S Leão, Larissa Lutz, Elizabeth A Marques, Amanda S Martins, Andreza F Martins, Elisa T Mendes, Euclimeire da S Neves, Thais C R L Nogueira, Maura S Oliveira, Joseani C Pascual, Dariane C Pereira, Vitor Hugo Perugini, Marcello T Ribeiro, Maria Helena P Rigatto, Verônica de F D Rocha, Jorge L M Sampaio, Daniel Sganzerla, Carlos Ernesto Ferreira Starling, Letícia O Sudbrack, João Paulo Telles, Eliana C Vespero, Camila M Wilhelm, Carolina H Yamada, Alexandre P Zavascki
• Ngôn ngữ: eng
• Ký hiệu phân loại: 912.01 Philosophy and theory
• Thông tin xuất bản: England : Lancet regional health. Americas , 2025
• Bộ sưu tập: NCBI
• ID: 170322

Tóm tắt

 BACKGROUND: Carbapenem-resistant METHODS: ASCENSION was a prospective, multicentre, observational study conducted in 14 hospitals from four of five Brazilian regions. FINDINGS: Between August 15, 2022, and August 14, 2023, 1350 isolates (1220 BSI episodes) were included. WPAP accounted for 38.8% (n = 524
  95% Confidence Interval 32.0-46.1) of all isolates, with CRE (19.3%) as the most frequent, followed by CRAB (9.6%), MRSA (4.9%), VRE (2.7%), and CRPA (2.4%). Incidence-density of all and WPAP isolates were 1.91 and 0.77/1000 patients-day, respectively. Carbapenem-resistant INTERPRETATION: A high frequency of WPAP bacteria, particularly CRKP and CRAB, were found in healthcare-associated BSIs in Brazil, posing them as a major public health problem in this country. FUNDING: National Council for Scientific and Technological Development, Brazil.