Unexpected Increase in Bone Mineral Density With Rapamycin and Low-Dose Naltrexone: A Case Report of a 52-Year-Old Woman With Osteopenia.

• Tác giả: Amy Britton, Girish Harinath, Stefanie Morgan, Sajad Zalzala
• Ngôn ngữ: eng
• Ký hiệu phân loại: 787.86 *Vihuelas
• Thông tin xuất bản: United States : Cureus , 2025
• Bộ sưu tập: NCBI
• ID: 170599

Tóm tắt

Osteopenia and osteoporosis are prevalent bone disorders characterized by reduced bone mineral density (BMD), leading to an increased risk of fractures. This case report presents a 52-year-old Caucasian female patient with osteopenia who experienced an unexpected 15.9% increase in lumbar spine BMD within two years after enrolling in a clinical trial involving low-dose rapamycin and subsequently starting low-dose naltrexone. This case potentially opens novel treatment strategies for bone density improvement in aging populations.