BACKGROUND: The aging population faces various health challenges, which has increased the burden on healthcare systems. Elderly individuals are more susceptible to urinary tract infections (UTIs), and rising bacterial resistance to antibiotics is a significant global issue. OBJECTIVES: This study compared the bacterial etiology and antibiotic sensitivity testing (AST) patterns of bacteria causing UTIs in elderly patients attending a tertiary care hospital across the intensive care unit (ICU), inpatient department (IPD), and outpatient department (OPD) and analyzed the association of the UTI with the presence of comorbidities and outcomes in the study population. METHODOLOGY: This retrospective study was conducted at the Department of Microbiology at a tertiary care hospital in Bhubaneswar. The demographic, clinical, and microbiological data were collected using a data abstraction form from the electronic medical record from January to December 2022. The study relied entirely on previously documented results. The urine samples received in the laboratory were processed following standard protocol. Identification and AST were done in the Vitek-2 (bioMérieux, Marcy-l'Étoile, France) automated system. AST was interpreted following the Clinical and Laboratory Standards Institute 2021. The Epi Info statistical software, version 7.2.3.1 (Centers for Disease Control and Prevention, Atlanta, GA), was used to analyze the data after loading it into a Microsoft Excel spreadsheet (Microsoft Corporation, Redmond, WA). The results were displayed as mean and standard deviation, frequencies, and percentages. A p value of less than 0.05 is considered statistically significant. Analysis of variance, chi-square test, and Fisher's exact test were employed as association tests. RESULTS: A total of 4,030 urine samples were processed for culture and sensitivity testing from the study population from January to December 2022. The data were retrospectively compiled and analyzed. The majority of samples (1,600
39.70%) were received from the ICU, followed by IPD (1,255
31.14%), and OPD (1,175
29.15%). Culture positivity was 1,560 (38.70%). The mean age of patients was 69.74 ± 7.52 years, ranging from 60 to 97 years. Males, 2,559 (63.50%), reported more UTIs than females. Chronic kidney disease (CKD, p = 0.0269) and hypertension (HTN, p = 0.0058), associated with UTI, were statistically significant. The most common bacterial isolate was CONCLUSION: The study showed that UTI was more prevalent in 60-69-year-old people and men.