Changes in Candidemia during the COVID-19 Pandemic: Species Distribution, Antifungal Susceptibility, Initial Antifungal Usage, and Mortality Trends in Two Korean Tertiary Care Hospitals.

• Tác giả: David Cho, Doyoung Han, Hae Seong Jeong, Sook-In Jung, Seung Ji Kang, Minji Kim, Sarah Kim, Seong Eun Kim, Uh Jin Kim, Ahrang Lee, Kyung-Hwa Park, Sung Un Shin, Jung Ho Yang
• Ngôn ngữ: eng
• Ký hiệu phân loại: 305.568 +Alienated and excluded classes
• Thông tin xuất bản: Korea (South) : Chonnam medical journal , 2025
• Bộ sưu tập: NCBI
• ID: 170982

Tóm tắt

 This study aimed to investigate changes in candidemia incidence, species distribution, antifungal susceptibility, initial antifungal use, and mortality trends in Korea before and during the COVID-19 pandemic. A retrospective analysis was conducted on candidemia cases from two tertiary care hospitals in Korea between 2017 and 2022. Data were compared between the pre-pandemic (2017-2019) and pandemic (2020-2022) periods. Statistical methods included incidence rate ratios (IRRs) and multivariate Cox regression to assess 30-day mortality risk factors. A total of 470 candidemia cases were identified, with 48.7% occurring pre-pandemic and 51.3% during the pandemic. While the overall incidence of candidemia remained similar across the two periods (IRR 1.15
  p=0.13), the incidence in intensive care units (ICUs) significantly increased during the pandemic (IRR 1.50
  p<
 0.01). The distribution of