Ultrasound Findings Suggestive of Malignancy in Thyroid Nodules Classified as Follicular Lesion of Undetermined Significance or Follicular Neoplasm based on the 2017 Bethesda System for Reporting Thyroid Cytopathology.

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Tác giả: Na Lae Eun, Soyoung Jeon, Heui Jin Jung, Jeong-Ah Kim, Hye Sun Lee, Eun Ju Son, Ji Hyun Youk

Ngôn ngữ: eng

Ký hiệu phân loại:

Thông tin xuất bản: Korea (South) : Journal of the Korean Society of Radiology , 2025

Mô tả vật lý:

Bộ sưu tập: NCBI

ID: 171350

PURPOSE: To identify US findings suggestive of malignancy in thyroid nodules with follicular lesions of undetermined significance (FLUS) or follicular neoplasm (FN) on fine-needle aspiration cytology (FNAC) and evaluate the diagnostic performance. MATERIALS AND METHODS: Seventy FLUS ( RESULTS: Microcalcification, homogeneous solid echotexture, and thickened rims were suggestive of malignancy. Our criteria showed a highest area under the ROC curve (AUC) value of 0.771, sensitivity of 97.14%, accuracy of 77.14%, positive predictive value of 93.33%, negative predictive value of 95.24%, and specificity of 97.14%. The criteria showed a significantly higher AUC value than K-TIRADS. CONCLUSION: US findings of homogenous solid portions, thick rims, and microcalcifications suggested malignancy in nodules with FLUS or FN on FNAC. These additional US findings could improve the diagnostic performance of K-TIRADS.
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