Exploiting Online Spatially Resolved Dynamic Light Scattering and Flow-NMR for Automated Size Targeting of PISA-Synthesized Block Copolymer Nanoparticles.

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Tác giả: Jonathan Booth, Richard A Bourne, Robin Capomaccio, Olivier J Cayre, Kudakwashe E Chingono, Nikil Kapur, Stephen T Knox, Elaine Martin, Nicholas Pedge, Peter M Pittaway, Nicholas J Warren

Ngôn ngữ: eng

Ký hiệu phân loại:

Thông tin xuất bản: United States : ACS polymers Au , 2025

Mô tả vật lý:

Bộ sưu tập: NCBI

ID: 171366

Programmable synthesis of polymer nanoparticles prepared by polymerization-induced self-assembly (PISA) mediated by reversible addition-fragmentation chain-transfer (RAFT) dispersion polymerization with specified diameter is achieved in an automated flow-reactor platform. Real-time particle size and monomer conversion is obtained via inline spatially resolved dynamic light scattering (SRDLS) and benchtop nuclear magnetic resonance (NMR) instrumentation. An initial training experiment generated a relationship between copolymer block length and particle size for the synthesis of poly(
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