Development of a Multienzyme Cascade for Salvianolic Acid A Synthesis from l-Tyrosine.

• Tác giả: Sheng Hu, Jun Huang, Changjiang Lv, Lehe Mei, Weijie Wang, Mingxi Zhang, Yuekai Zhang, Weirui Zhao, Jiayi Zhong
• Ngôn ngữ: eng
• Ký hiệu phân loại: 612.647 Development of fetus
• Thông tin xuất bản: United States : ACS omega , 2025
• Bộ sưu tập: NCBI
• ID: 172021

Tóm tắt

Salvianolic acid A (SAA) has an important application value for preventing and treating cardiovascular diseases. In this study, we developed a novel multienzyme cascade system for the efficient biosynthesis of SAA, utilizing l-tyrosine (l-Tyr) as a cost-effective and stable starting material. The cascade system incorporated four enzymes: membrane-bound l-amino acid deaminase from