BACKGROUND: Diabetes mellitus has become one of the major pandemics of the 21 AIM: To analyse nursing interventions in recent years through a systematic review and meta-analysis and to propose improvements in care plans. METHODS: This study conducted a systematic review and meta-analysis of the impact of nursing interventions on quantitative glycaemic variables, such as glycated haemoglobin and fasting plasma glucose. RESULTS: After confirming that the combined effect of all studies from the past 5 years positively impacts quantitative variables, a descriptive analysis of the studies with the most significant changes was conducted. Based on this, an improvement in diabetic patient care protocols has been proposed through follow-up plans tailored to the patient's technological skills. CONCLUSION: The combined results obtained and the proposal for improvement developed in this manuscript could help to improve the quality of life of many people around the world.