Beyond traditional medications: exploring novel and potential inhibitors of trypanothione reductase (LmTr) of Leishmania parasites.

• Tác giả: Faris F Aba Alkhayl, Abida, Mohammad Alrofaidi, Mohammed Sanad Alshammari, Abdullah R Alzahrani, Syed Mohammed Basheeruddin Asdaq, M Afroz Bakht, Lina Eltaib, Mohd Imran, Muhammad Sarfraz
• Ngôn ngữ: eng
• Ký hiệu phân loại: 296.1138 Sources
• Thông tin xuất bản: England : Journal of biomolecular structure & dynamics , 2025
• Bộ sưu tập: NCBI
• ID: 173245

Tóm tắt

The trypanothione reductase enzyme, which neutralizes the reactive oxygen species produced inside the macrophages to kill the parasites, is one of the evasion strategies Leishmania uses to survive inside the cells. The vitality of the parasite depends on