The effect of the size of the new contour neurovascular device for altering intraaneurysmal flow.

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Tác giả: Johannes Hensler, Jan-Bernd Hövener, Olav Jansen, Naomi Larsen, Sönke Peters, Andrey N Pravdivtsev, Mariya S Pravdivtseva, Fritz Wodarg

Ngôn ngữ: eng

Ký hiệu phân loại: 546.677 *Indium

Thông tin xuất bản: United States : Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences , 2025

Mô tả vật lý:

Bộ sưu tập: NCBI

ID: 173554

BACKGROUND: Recently, a novel intrasaccular device (contour neurovascular system, contour) was introduced to treat intracranial aneurysms. Contour is placed at thе aneurysm neck and reduces the intraaneurysmal blood inflow. Contour comes in a range of sizes to target different aneurysms. The efficiency of altering flow with contour and the effect of device size have not yet been investigated. Therefore, we studied the effect of the device size with patient-based aneurysm models using 2D digital subtraction angiography (DSA). METHODS: Three patient-based aneurysm models with necks ranging from 2.7 to 9.7 mm were produced, providing standardized testing conditions. Contours with diameters of 5, 11, and 14 mm were implanted into the models, four of each size. 2D DSA images were acquired before and after implanting contour (15 frames/s, manual contrast injection). After injecting angiographic contrast agent, the DSA signal was recorded over time to calculate the contrast washout time (WOT), which is a measure of flow diversion efficiency. RESULTS: All contour devices caused contrast agent stasis and increased WOT in aneurysm sac ( CONCLUSION: The 5-mm contour showed the longest WOT value in our study, while no apparent difference between 11-mm contour and 14-mm contour was found.
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