Sexual dysfunction in dichlorvos-exposed male Wistar rat is ameliorated by curcumin and associated with the upregulation of testosterone.

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Tác giả: R E Akhigbe, O R Kolawole, A A Oladipo, A Olayioye, W A Saka

Ngôn ngữ: eng

Ký hiệu phân loại: 220.404 Textual criticism and word studies

Thông tin xuất bản: Germany : Naunyn-Schmiedeberg's archives of pharmacology , 2025

Mô tả vật lý:

Bộ sưu tập: NCBI

ID: 174058

 Dichlorvos is an organophosphate pesticide that is commonly used for agricultural and domestic control of pests and insects. Despite its usefulness, it exerts reproductive toxicity and induces male sexual dysfunction. On the other hand, curcumin has been reported to improve sexual dysfunction. However, till date, no study has reported the impact of curcumin on dichlorvos-induced sexual dysfunction. This study investigated the effect and associated mechanism of curcumin on dichlorvos-induced sexual dysfunction. Thirty-two male Wistar rats were randomized into four groups
  the control (1 mL of olive oil), curcumin-treated (100 mg/kg), DDVP-treated (98.54 g/m
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