Sulfur-based aqueous batteries (SABs) are regarded as promising candidates for safe, low-cost, and high-energy storage. However, the sluggish redox kinetics of polysulfides pose a significant challenge to the practical performance of SABs. Herein, we report a unique redox regulation strategy that leverages thiosulfate-mediated ligand-chain interaction to accelerate the polysulfide redox process (S