"Better Late Than Never"-Late-Onset Genotype-Negative Congenital Long QT Syndrome: Case Report and Review.

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Tác giả: Chaminda Sella Kapu, Clement Tan, Vaikunthan Thanabalasingam, Zhihua Zhang

Ngôn ngữ: eng

Ký hiệu phân loại: 920.71 Men

Thông tin xuất bản: England : Clinical case reports , 2025

Mô tả vật lý:

Bộ sưu tập: NCBI

ID: 176113

Congenital long QT syndrome (LQTS) is a genetic disorder causing prolonged QT intervals and an increased risk of arrhythmias and sudden cardiac death. With 25% of cases lacking known genetic mutations, diagnosis and treatment can be challenging. We present a successfully managed case of late-onset genotype-negative phenotype-positive LQTS presenting as palpitations, complicated by a single event of polymorphic ventricular tachycardia, followed by a review of the literature. This case underscores the gaps in understanding congenital long QT syndrome, especially in genotype-negative cases, and highlights the need for ongoing research for risk assessment and effective management to prevent fatal cardiac events.
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