Studying Metabolic Brain Connectivity Using 2-Deoxy-2-[18F]Fluoro-D-Glucose Dynamic Positron Emission Tomography at the Single-subject Level.

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Tác giả: Veerle De Herdt, Melissa Lajtos, Sara Neyt, Robrecht Raedt, Christian Vanhove

Ngôn ngữ: eng

Ký hiệu phân loại: 070.48346 Journalism

Thông tin xuất bản: United States : Journal of visualized experiments : JoVE , 2025

Mô tả vật lý:

Bộ sưu tập: NCBI

ID: 1765

To this day, metabolic brain connectivity is mostly studied on a group level through the acquisition of static positron emission tomography (PET) data of multiple subjects. Our research groups are currently studying changes in metabolic connectivity across multiple time points following an intracerebral hemorrhage on an intrasubject level in rats. To investigate intrasubject metabolic brain connectivity, temporal information of the tracer uptake in different brain regions is required, which can be achieved through dynamic PET. In this publication, we give a detailed description of our data acquisition and analysis protocol. Dynamic PET data of the rat brain are acquired on a dedicated preclinical PET system using 2-deoxy-2-[
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