Nickel-Catalyzed Cross-Electrophile Coupling of Aryl Triflates with Alkyl Halides: Mechanism-Informed Design of More General Conditions.

• Tác giả: Benjamin N Ahern, Matthew J Goldfogel, Ilia A Guzei, Seoyoung Kim, Daniel C Salgueiro, Daniel J Weix
• Ngôn ngữ: eng
• Ký hiệu phân loại: 341.763 Labor
• Thông tin xuất bản: United States : Journal of the American Chemical Society , 2025
• Bộ sưu tập: NCBI
• ID: 176639
• Chủ đề: 1. Nickel; 2. Catalyzed; 3. Cross

Tóm tắt

Aryl triflates make up a class of aryl electrophiles that are available in a single step from the corresponding phenol. Despite the known reactivity of nickel complexes for aryl C-O bond activation of phenol derivatives, nickel-catalyzed cross-electrophile coupling using aryl triflates has proven challenging. Herein, we report a method to form C(sp