Do not sleep on vitamin D: vitamin D is associated with sleep variability in apparently healthy adults.

• Tác giả: Meral N Culver, Catherine L Garrett, Zach J Hutchison, Braxton A Linder, Delaney E Lyons, Jessica N McNeil, Austin T Robinson
• Ngôn ngữ: eng
• Thông tin xuất bản: United States : American journal of physiology. Regulatory, integrative and comparative physiology , 2025
• Bộ sưu tập: NCBI
• ID: 177377

Tóm tắt

 Vitamin D is associated with sleep quality and duration, but it is unclear whether vitamin D status influences sleep variability. Therefore, we sought to determine whether vitamin D status was associated with sleep variability in healthy adults. We assessed objective sleep, including timing and duration standard deviation (SD) using the Philips Actiwatch Spectrum and subjective sleep quality using the Pittsburgh Sleep Quality Index (PSQI) in 130 adults. We measured plasma 25(OH)D concentration to assess vitamin D. We used one-way ANOVAs and Kruskal-Wallis tests to compare sleep in participants characterized as vitamin D deficient (<
 20 ng/mL), insufficient (21-29 ng/mL), and sufficient (>
 30ng/mL). We used covariate-adjusted linear regression to assess associations between vitamin D status and sleep metrics. We compared differences in "low" and "high" sleep variability based on vitamin D status using the Chi-squared test. There was an effect of vitamin D status on sleep timing SD (Kruskal-Wallis,