Difunctional oxidatively cleavable alkenyl boronates: application to cellular peroxide sensing from a fluorophore-quencher pair.

• Tác giả: Savannah Albright, Alexander Deiters, Grace M Fleury, Paul E Floreancig, Brittany M Klootwyk
• Ngôn ngữ: eng
• Ký hiệu phân loại: 331.2574 Conditions of employment
• Thông tin xuất bản: England : Chemical communications (Cambridge, England) , 2025
• Bộ sưu tập: NCBI
• ID: 177715

Tóm tắt

This manuscript describes the development of difunctional alkenyl boronates that contain an oxidatively releasable cargo and an amine for attaching to groups that can improve physical properties or enhance cellular targeting. The design is applied to a FRET-based system that delivers a selective fluorescence response in oxidatively stressed cells.