ESRRA (estrogen related receptor, alpha) induces ribosomal protein RPLP1-mediated adaptive hepatic translation during prolonged starvation.

• Tác giả: Kabilesh Arul, Boon-Huat Bay, Karine Gauthier, Sujoy Ghosh, Vincent Giguere, Priyanka Gupta, Lena Ho, Nah Jiemin, Donald P McDonnell, Sung-Hee Park, Suganya Sakthivel, Reddemma Sandireddy, Brijesh K Singh, Keziah Tikno, Madhulika Tripathi, Lijin Wang, Yajun Wu, Paul M Yen, Jin Zhou
• Ngôn ngữ: eng
• Ký hiệu phân loại: 796.9626 Ice and snow sports
• Thông tin xuất bản: United States : Autophagy , 2025
• Bộ sưu tập: NCBI
• ID: 179266

Tóm tắt

 Protein translation is an energy-intensive ribosome-driven process that is reduced during nutrient scarcity to conserve cellular resources. During prolonged starvation, cells selectively translate specific proteins to enhance their survival (adaptive translation)
  however, this process is poorly understood. Accordingly, we analyzed protein translation and mRNA transcription by multiple methods