OBJECTIVE: This case report discusses the effective management of a full-thickness rotator cuff injury using Ayurvedic treatment modalities in a 65-year-old patient who declined surgical intervention. BACKGROUND: After sustaining an injury from an external impact, the patient experienced severe shoulder pain and reduced mobility. Clinical and radiological assessments confirmed a full-thickness supraspinatus tear. INTERVENTION: Opting for a non-surgical approach, the treatment plan included a series of Ayurvedic polyherbal formulations and topical applications along with a set of guided physical rehabilitation. RESULTS: Remarkably, the patient achieved complete symptomatic relief and regained full shoulder function within five months. This case underscores the potential of Ayurvedic medicine as an alternative and adjunct therapeutic strategy for managing rotator cuff injuries, advocating for broader research into its clinical applications and underlying therapeutic mechanisms in orthopedic ailments. CONCLUSION: This case report demonstrates improved quality of care by integrating Ayurvedic therapies with rehabilitative exercise. This suggests a potential change in practice by incorporating complementary therapies like Ayurveda to manage rotator cuff injury.