Predictive factors for 30-day mortality after polymyxin B treatment of carbapenem-resistant Gram-negative bacilli infections.

• Tác giả: Shuo Cheng, Weihong Ge, Xuemei Luo, Xinyue ShuLai, Huimin Zhou, Simin Zhou
• Ngôn ngữ: eng
• Ký hiệu phân loại: 331.7 Labor by industry and occupation
• Thông tin xuất bản: Canada : International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases , 2025
• Bộ sưu tập: NCBI
• ID: 182263

Tóm tắt

OBJECTIVES: This study aimed to investigate the associated factors predicting 30-day mortality of carbapenem-resistant Gram-negative bacilli (CR-GNB) infections, with focus on polymyxin B AUC METHODS: This prospective cohort study included patients with CR-GNB infections from January 2022 to January 2024. The primary outcome was 30-day mortality. Classification and regression tree (CART) analysis was used to calculate the AUC RESULTS: We enrolled 107 patients, among which 30-day mortality occurred in 31 (29.0%) cases. The CART-derived AUC CONCLUSIONS: Polymyxin B AUC