Infant anaphylaxis, a life-threatening condition, remains poorly understood due to limited research in this vulnerable population. Financial, ethical, and regulatory barriers hinder pediatric research, leaving critical gaps in knowledge. Physician advocacy is vital in addressing these challenges by urging policymakers to prioritize increased funding for pediatric studies at national and international levels. Enhanced investment would support improved diagnosis and management of poorly understood conditions early in life, offering better outcomes for infants and their families. By advancing research in this area, we can address significant unmet needs and foster healthier futures for our youngest patients.