OBJECTIVES: This study aimed to investigate the impact of socioeconomic status on survival in Chinese patients with acral melanoma. METHODS: We collected clinical and socioeconomic information of 298 primary acral melanoma patients and performed Kaplan-Meier curves, log-rank tests, Cox proportional hazards models, and Pearson's chi-squared tests to evaluate the relationships between clinical characteristics, socioeconomic factors, and survival outcomes. RESULTS: Among the clinical characteristics, age, gender, stage, Breslow thickness, and primary tumor site significantly impacted survival in acral melanoma patients ( CONCLUSION: Socioeconomic level is associated with survival in Chinese acral melanoma patients. However, this association may be attributable to Breslow thickness rather than socioeconomic status itself.