PURPOSE: This study aimed to investigate the predictors of successful weaning from veno-venous extracorporeal membrane oxygenation (VV-ECMO) among patients with severe acute respiratory distress syndrome (ARDS) in our centre. METHODS: The clinical data of patients with severe ARDS who were treated with VV-ECMO between January 2019 and January 2022 were retrospectively analysed. Due to the outcomes of weaning from extracorporeal membrane oxygenation (ECMO), the considered patients with ARDS were divided into a successful weaning group and an unsuccessful weaning group. Logistic regression analysis was employed to evaluate predictors for successful VV-ECMO weaning among patients with severe ARDS. RESULTS: A total of 65 patients with severe ARDS were included for analysis. Among them, 31 (47.69%) patients were grouped into the successful weaning group, while 34 (52.30%) patients were grouped into the unsuccessful weaning group. Univariate analysis showed that Age (odds ratio [OR] =0.939
95% confidence interval [CI] =0.896-0.983
CONCLUSION: In conclusion, in severe ARDS patients, lower APACHE II scores predicted successful wean from VV-ECMO.