Discovery of Novel Quinazolinone-2-carbohydrazide Derivatives as Effective Succinate Dehydrogenase Inhibitors and Biosafety Assessment on Rice and Zebrafish.

• Tác giả: Xiaoping Bao, Hong Li, Sha Li, Shengping Liu, Taisen Yan
• Ngôn ngữ: eng
• Ký hiệu phân loại: 567.9153 Reptilia
• Thông tin xuất bản: United States : Journal of agricultural and food chemistry , 2025
• Bộ sưu tập: NCBI
• ID: 186666

Tóm tắt

To develop potent and safe antifungal agents in agriculture, a total of 48 novel quinazolinone-2-carbohydrazide derivatives were designed and synthesized based on the pharmacophore hybridization method. The bioassay results demonstrated that many compounds exhibited powerful and broad-spectrum inhibition activities