Biomarkers of radioresistance in head and neck cancer: a new beginning.

• Tác giả: Yuan James Rao
• Ngôn ngữ: eng
• Ký hiệu phân loại: 617.51 *Head
• Thông tin xuất bản: United States : Clinical cancer research : an official journal of the American Association for Cancer Research , 2025
• Bộ sưu tập: NCBI
• ID: 187035

Tóm tắt

The development of biomarkers of radioresistance in head and neck cancer may help personalize treatment. This commentary puts in context the findings of a secondary analysis of NRG/RTOG 9512, a trial of fractionation in T2N0 glottic cancer, which observed that NFE2L2/KEAP1/CUL3 mutations are correlated with local recurrence and disease-free survival.