Identification of polycystin 2 missense mutants targeted for endoplasmic reticulum-associated degradation.

• Tác giả: Jeffrey L Brodsky, Michael J Caplan, Marcelo D Carattino, Nikolay P Gresko, Christopher J Guerriero, Luke J Kantz, Katherine G Sharp
• Ngôn ngữ: eng
• Ký hiệu phân loại: 230.0071 Christianity Christian theology
• Thông tin xuất bản: United States : American journal of physiology. Cell physiology , 2025
• Bộ sưu tập: NCBI
• ID: 189163

Tóm tắt

Autosomal dominant polycystic kidney disease (ADPKD) is a common genetic disorder leading to end-stage renal disease. ADPKD arises from mutations in the