Towards a neurodevelopmental model of bipolar disorder: a critical review of trait- and state-related functional neuroimaging in adolescents and young adults.

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Tác giả: Hilary P Blumberg, Lejla Colic, Danielle A Goldman, Jihoon A Kim, Anjali Sankar

Ngôn ngữ: eng

Ký hiệu phân loại:

Thông tin xuất bản: England : Molecular psychiatry , 2025

Mô tả vật lý:

Bộ sưu tập: NCBI

ID: 189552

Neurodevelopmental mechanisms are increasingly implicated in bipolar disorder (BD), highlighting the importance of their study in young persons. Neuroimaging studies have demonstrated a central role for frontotemporal corticolimbic brain systems that subserve processing and regulation of emotions, and processing of reward in adults with BD. As adolescence and young adulthood (AYA) is a time when fully syndromal BD often emerges, and when these brain systems undergo dynamic maturational changes, the AYA epoch is implicated as a critical period in the neurodevelopment of BD. Functional magnetic resonance imaging (fMRI) studies can be especially informative in identifying the functional neuroanatomy in adolescents and young adults with BD (BD
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