Tire wear particles (TWPs) are considered the one of most significant non-exhaust particle emission sources from vehicles. However, there is a lack of research on the emission characteristics of TWPs based on typical driving information. In this work, we used a high-dynamic outside wheel test platform to conduct tire wear tests on multiple types of tires based on a novel test cycle and comprehensively analyzed the differences in their emission characteristics while considering various factors, such as front/rear tire and tire type. We conducted a chemical composition analysis of TWPs. There are certain differences in the mass size distributions of TWPs from different types of tires. The emissions of PM