OBJECTIVE: The purpose of this study was to (1) examine the relationship between perceived work-related fatigue and performance fatigability, and (2) assess the impact of percent body fat (%BF) on perceived fatigue constructs in career firefighters. METHODS: Thirty-nine career firefighters completed body composition testing, the Occupational Fatigue Exhaustion Recovery (OFER15) scale assessing three subscales of work-related fatigue (acute fatigue, chronic fatigue, and inter-shift recovery), and maximal leg extensor isometric strength testing prior to and following an isotonic fatiguing protocol. RESULTS: Performance fatigability was not associated with any of the OFER15 perceived work-related fatigue variables ( P ≥ 0.513). Greater %BF was associated with greater %∆ peak torque ( r = -0.41, P = 0.010) but none of the OFER15 perceived work-related fatigue variables ( P ≥ 0.638). CONCLUSIONS: Performance fatigability was not associated with OFER15 perceived work-related fatigue, and greater adiposity negatively impacted performance fatigability but not perceived fatigability.